Why It Works

 

Chest pain is often the key indicator of a life-threatening acute cardiac event.  Or the pain could stem from an entirely benign condition.  Which is it?  Should the Emergency Department (ED) physician send the patient home, watchfully wait, or admit them to the hospital? The consequences of ignoring an acute myocardial infarction can be dire – avoidable death.  But misdiagnosing noncardiac disease leads to needless expense and patient concern, wasting limited medical resources and scarce hospital beds.  What if a computer decision-making tool could consider all the symptoms and tests, assessing all feasible diagnoses?  Then carefully weigh all the evidence to quantify its differential diagnosis?  And simply explain its reasoning in an intuitive way to the physician? 


Welcome to Vaizian™, the Bayesian decision-making tool for medical diagnostic professionals.  The Vaizian software considers all symptoms and signs, the ECG, and lab tests.  The computer uses probability to calculate likelihood ratio (LR) evidence values.  Vaizian weighs all the medical evidence for each diagnosis by adding up the log(LR) values – both for and against.  

Uniquely, Vaizian can visually explain its reasoning to the ED physician.  What is the evidence for each symptom or test, at each considered diagnosis?  Vaizian displays these evidence values in a heatmap, for rapid visual assessment of diagnoses and the contrasts between them.  The user can probe the evidence, visually exploring underlying probabilities and error rates.  

Vaizian is built on the advanced TrueAllele® technology, used by forensic DNA scientists for thorough probabilistic genotyping that delivers accurate LR match values.  Used in the World Trade Center disaster, and in tens of thousands of criminal cases, the innovative TrueAllele system helps find the guilty and free the innocent.  

Using Vaizian technology, ED physicians can make better decisions to help their patients.  Physician assistants, nurse practitioners, and medical students can use Vaizian as well.  Knowledgeable, intuitive, understandable Vaizian diagnosis scrutinizes all the patient data to consider all diagnostic possibilities.  Better diagnosis leads to better outcomes.  

When your patient enters the ED, use Vaizian to quickly decide where they go next.  Home, hospital, or somewhere in between.  Evidence-based reasoning – with intuitive visual explanations – lets you use all of your patient data, all of the time.